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中国生物医学工程学会
北京玛格泰克科技发展有限公司
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2020 Vol. 29, No. 2
Published: 2020-06-01
1
Research on Tongue Image Collection and Analysis Based on Smartphone
Xuemin Wang, Yingying Sun, Qiuyue Wang, Zhifeng Yu
Tongue diagnosis is a diagnostic method to understand the physiological functions and pathological changes of the human body by observing human tongue quality, tongue coating, and sublingual collateral veins. Tongue elephant research is an important part of objective Chinese medicine. Based on the research of tongue image analysis method, the design of a tongue image collection analysis system based on the smartphone platform was demonstrated. This research uses a smartphone camera to collect tongue images, upload them to the server and complete tongue image analysis on the server. Finally, the tongue image analysis results are generated, and the results are transmitted from the server to the smartphone mobile terminal. We used HTTP protocol for communication between mobile client and server. We asked professional TCM doctors to evaluate the results of tongue analysis in 100 cases, and the final anastomosis rate was above 80%. This study fills in the gaps in the mobile platform of objectification of tongue diagnosis, which is conducive to the use of mobile phones to collect tongue images anytime, anywhere, and to conveniently share the results of tongue diagnosis with physicians. With an Internet connection, users can use their smartphones to remotely diagnose their tongues, who can store and generate their own personal diagnostic reports.
2020 Vol. 29 (2): 1-9 [
Abstract
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116
)
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10
Application of a Quality Assurance Solution Based on an Electronic Field Imaging Device in Linac
Tianlong Ji, Lu Sun, Hao Shen, Guang Li
Objective
To test a quality assurance (QA) DVS solution-DVS based on a linac electronic field imaging device (EPID) and evaluate its accuracy and ease of use.
Methods
All of the QA items that do not require the dedicated QA phantom in the DVS solution were tested. Test methods were chosen based on the test items: for the collimator rotation center, the coincidence of the radiation and mechanical, mechanical flatness/symmetry and MLC transmission were compared with the existing QA solution; for the leaf position accuracy and repeatability, the original preset beam fields and fields adjusted by 1 mm were compared.
Results
The collimator rotation center by the DVS solution is similar to the existing solution. For coincidence of radiation and mechanical, the DVS solution provides more data, including 3D distance. For the flatness / symmetry property, the DVS solution can display more graphics, but the overall data is less than the ion-chamber matrix solution. The DVS solution can directly obtain the MLC transmission value and quickly and intuitively measure the position accuracy of the MLC. However, the repeatability is slightly worse.
Conclusion
The DVS solution can improve the QA work efficiency and reduce workload, and there are more opportunities for improvement.
2020 Vol. 29 (2): 10-16 [
Abstract
] (
73
)
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17
Correlation between Carotid Plaque Characteristics without Operative Indication and Ischemic Stroke
Qian Wang, Sibo Liu, Anni Long, Jingzhe Liu, Xiaowei Zhang, Lei Li
Objective
To access the correlations between characteristics of carotid plaque in MRI and ischemic stroke in patients with ≤50% carotid artery stenosis.
Methods
A total of 43 patients with ≤50% carotid artery stenosis were selected for ultrasound from September 2014 to February 2016. A further test using magnetic resonance (MR) black blood imaging examination were carried out to distinguish the anatomy of the vessel as well the composition of the atherosclerotic plaque with remarkable details. The relationship between carotid plaque characteristics in MRI and other risk factors of patients with ischemic stroke was analyzed by univariate and multivariate analysis.
Results
The mean follow-up time was 11.8 months. During the follow-up period, 4 of the 43 individuals experienced an ipsilateral ischemic stroke. Kaplan-Meier survival analysis showed the mean ischemic stroke free survival of patients with coronary heart disease (CHD) was significantly shorter than that in patients without CHD, which were 12.1 months and 18.7 months respectively (
P
=0.029). The mean ischemic stroke free survival of patients with intra-plaque hemorrhage (IPH) was significantly shorter than that in patients without IPH, which were 14.3 months and 18.6 months respectively (
P
=0.001). COX regression analysis showed that coronary heart disease (
HR
=27.4; 95% CI, 1.6-464.3;
P
=0.022) and IPH (
HR
=18.2; 95% CI, 2.7-123.3;
P
=0.003) were independent risk factors for ischemic stroke.
Conclusion
For patients with carotid artery stenosis ≤50%, IPH of carotid plaques and CHD are independent risk factors for ischemic stroke.
2020 Vol. 29 (2): 17-24 [
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57
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25
Comparison of Heart Rate Variability between Normoxia and Hypobaric Hypoxia Exposure
Yuanyuan Liu, Zhengtao Cao, Mengsun Yu, Jun Yang, Binhua Wang, Yingying Ma
This study aimed to use the sample entropy (SampEn) method to compare the difference between normoxia and hypobaric hypoxia exposure in heart rate variability. Eight healthy male volunteers were included in this research. For each subject, electrocardiography and finger pulse signal were recorded to obtain the heart rate time series. The SpO
2
signal was collected at the same time. In normoxia or hypobaric hypoxia 4300 m section, the segment of RR time series from the second 5 min episode (from the 6th to the 10th min) was chosen for the SampEn calculation. The differences between normoxia and hypobaric hypoxia states were analyzed. Results showed that a significant difference exists in SampEn between two states (normoxia 0.54±0.05 vs hypobaric hypoxia 4300 m exposure 0.46±0.05), indicating the regulatory mechanisms of autonomic nervous system from a nonlinear perspective.
2020 Vol. 29 (2): 25-30 [
Abstract
] (
118
)
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31
Clinical Analysis of Children with Corpus Callosum Pressure Lesion Syndrome
Caimei Lin, Xiaolan Zheng, Huihong Su
Objective
The aim of the study was to investigate the clinical features, imaging features, and prognosis of splenium of the corpus callosum in children in order to improve the clinical understanding.
Methods
The clinical data and imaging data of 30 children with splenium of the corpus callosum treated in Xiamen Children’s Hospital from June 2017 to October 2019 were retrospectively analyzed.
Results
Thirty children aged from 19 months to 12 years, with an average age of 5.4 years were included in the study; all had fever and other prodromal infections at acute onset, including 15 cases of respiratory tract infection, 9 cases of digestive tract infection, and 6 cases of central nervous system infection. According to cranial magnetic resonance imaging (MRI) findings, 23 cases had type I syndrome and 7 cases had type II syndrome; 23 children had clinical symptoms disappeared after 1 week, 7 children had clinical symptoms disappeared after 1 month, and 23 children had the abnormal signal disappeared after 2 weeks of reexamination, and the abnormal signal disappeared completely after 1 month of reexamination in 7 children.
Conclusion
Central nervous system infection is also a predisposing factor for the pressor syndrome of the corpus callosum in children in addition to upper respiratory tract infection and gastrointestinal tract infection, and all children have good prognosis.
2020 Vol. 29 (2): 31-36 [
Abstract
] (
56
)
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37
Research Progress of Esomeprazole and its Potential Risk for Administration
Fotian Xie, Yi Lv
Esomeprazole, one of the proton pump inhibitors (PPIs), has been widely used in acid-related diseases, such as gastro-esophageal reflux disease and Helicobacter pylori infection. Compared with other PPIs, esomeprazole has higher acid control efficiency, bioavailability, stability, and less interindividual variation depending on its pharmacokinetic properties.Esomeprazole was considered safe for long-term administration. However, several recent studies have contradicted its absolute safety, and some detrimental cases have been reported in some special groups, such as pregnant women and patients with liver cirrhosis. Because acid-related diseases usually require long-term therapy and esomeprazole inhibits CYP2C19 enzyme that increases the probability of drug-drug interaction, these risks have become a concern. Recent studies have shown that esomeprazole not only inhibits acid secretion, but also exhibits acid-independent effects in inflammatory conditions. Esomeprazole can modulate NF-κb activation to resist tissue oxidation and apoptosis in gastric ulcer. In CCL4-induced liver fibrosis, esomeprazole improves oxidative stress, fibrogenesis, and apoptosis, but the mechanism still remains unclear. This review summarized the property of esomeprazole and its potential risk for administration, and its latest research progress, which may facilitate clinicians to better use and avoid the potential risks.
2020 Vol. 29 (2): 37-45 [
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] (
92
)
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