|
|
|
| Clinical Analysis of Children with Corpus Callosum Pressure Lesion Syndrome |
| Caimei Lin, Xiaolan Zheng, Huihong Su |
| Department of Neurology, Xiamen Children’s Hospital, Xiamen Fujian 361000, China |
|
|
|
|
Abstract Objective The aim of the study was to investigate the clinical features, imaging features, and prognosis of splenium of the corpus callosum in children in order to improve the clinical understanding. Methods The clinical data and imaging data of 30 children with splenium of the corpus callosum treated in Xiamen Children’s Hospital from June 2017 to October 2019 were retrospectively analyzed. Results Thirty children aged from 19 months to 12 years, with an average age of 5.4 years were included in the study; all had fever and other prodromal infections at acute onset, including 15 cases of respiratory tract infection, 9 cases of digestive tract infection, and 6 cases of central nervous system infection. According to cranial magnetic resonance imaging (MRI) findings, 23 cases had type I syndrome and 7 cases had type II syndrome; 23 children had clinical symptoms disappeared after 1 week, 7 children had clinical symptoms disappeared after 1 month, and 23 children had the abnormal signal disappeared after 2 weeks of reexamination, and the abnormal signal disappeared completely after 1 month of reexamination in 7 children. Conclusion Central nervous system infection is also a predisposing factor for the pressor syndrome of the corpus callosum in children in addition to upper respiratory tract infection and gastrointestinal tract infection, and all children have good prognosis.
|
|
|
|
|
|
[1] Tada H, Takahashi J, Barkovich AJ,et al.Clinically mild encephalitis/encephalopathy with a reversible splenial lesion[J].Neurology,2004,63:1854-1858.
[2] Garcia-Monco JC, Cortina IE, Ferreira E,et al.Reversible splenial lesion syndrome(RESLES): What’s in a name[J].J Neuroimaging, 2011,21(2):1-14.
[3] Hoshino A, Saitoh M, Oka A,et al.Epidemiology of acute encephalopathy in Japan, with emphasis on the association of viruses and syndrome[J]. Brain Dev, 2012,34(5):337-343.
[4] Marsala SZ, Antichi E, Pistacchi M,et al.Mild encephalitis with a reversible splenial lesion: A clinical benign condition,often underrecognized–clinical case and literature review[J].J Neurosci Rural Pract, 2017,8:281-283.
[5] Shi Bc, Li J, Jiang Jw,et al.Mild encephalitis/encephalopathy with a reversible splenial lesion secondary to encephalitis complicated by hyponatremia:a case report and literature review[J]. Medicine,2019,98:47(e17982).
[6] Zhao Lirong,Wu Hua,Guo Mangmang,et al.A case of mild encephalitis/encephalopathy with reversible splenic lesions of corpus callosum and literature review[J].Chinese Journal of Pediatrics,2014,52(3):218-222.
[7] Kim SS, Chang KH, Kim ST,et al. Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity[J]. AJNR Am J Neuroradiol,1999,20(1):125-129.
[8] Gao Yang, Zou Liping, Wang Jianjun,et al.Clinical characteristics of mild encephalitis or encephalopathy with reversible lesions of splenium callosum in children[J].Chinese Journal of Practical Pediatrics,2016,31(1):56-59.
[9] Nan Zaiyuan, Wang Chunyu, Zhang Zhe,et al.Clinical characteristics and literature review of 32 children with reversible splenic lesions syndrome[J].Chinese Journal of Integrated Traditional and Western Medicine Pediatrics,2019,11(5):435-437.
[10] Pei Jiangshan, Chen Tianfeng, WanG Qiang. Clinical and cranial MRI findings of 27 children with reversible splenic lesions syndrome[J].Modern Medical Imaging,2019,28(7):1618-1620.
[11] Radiology department of Beijing Children's Hospital. Journal of practical pediatric radiology is published in[J].Chinese Journal of Radiology,2000,34(9):587.
[12] Zhang Yang, Chen Weian, Bi Yong,et al.Clinical analysis of 107 patients with mild clinical symptoms of encephalitis/encephalopathy with reversible lesions in splenium of corpus callosum[J].Chinese General Practitioners,2014,12(6):875-878.
[13] Zhang Jing, Li Tao, Yin Guangheng,et al.MRI findings of reversible splenium callosum syndrome in children[J].Chinese Journal of Radiology, 2015,49(12):927-930.
[14] Xin Yongtong, Lin Xiumeng.Clinical and literature analysis of reversible splenic lesion syndrome[J].Nerve Injury and Functional Reconstruction, 2019,14(8):395-398.
[15] Wang Fang, Shao Jianbo, Zhou Jing,et al.MRI diagnosis and differential diagnosis of reversible splenium callosum syndrome in children[J].Imaging Diagnosis and Interventional Radiology,2015,27(3):3767-3770.
[16] Pei Jiangshan, Chen Tianfeng, Wang Qiang. Clinical and cranial MRI findings of 27 children with reversible splenic lesions syndrome[J].Modern Medical Imaging, 2019,28(7):1618-1620.
[17] Yuan Xin, Li Rui, Chen Yongkang, et al.Clinical analysis of reversible splenic lesion syndrome[J].Chinese Journal of Practical Neurology, 2018,21(23):2584-2591.
[18] Yang Jun, Xu Wenli. Clinical and MRI analysis of reversible splenic lesion syndrome[J].Modern Practical Medicine, 2018,30(11):1504-1505, 1509.
[19] Song Lifang, Chen Guohong, Wang Li, et al.Clinical analysis of 20 children with reversible splenic lesion syndrome[J].Chinese Journal of Practical Neurology, 2017,20(7):43-45.
[20] Zhang Xinxin, Sun Wenxiu, Gao Yuxing,et al.Clinical analysis of reversible splenium callosum syndrome in children[J].Journal of Clinical Pediatrics, 2015,33(11):924-928. |
|
|
|
