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中国生物医学工程学会
北京玛格泰克科技发展有限公司
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2016 Vol. 25, No. 4
Published: 2016-12-01
Research papers
Review
Research papers
139
Study on Spot Addressing and Segmentation Method for Microarray Image
LIU Quan-jin, ZHU Xing-yue, ZHAO Zhi-min
This paper presents a novel method of spot addressing and segmentation about the foreground segmentation of microarray image. In this paper, a spot addressing method based on particle swarm optimization (PSO), algorithm is proposed to have a further search for the center coordinate and radius of the spot whose region is determined by the projection method. Then, a foreground segmentation method is put forward to make the spot foreground segmentation based on the center coordinate and radius of the spot. The spot addressing and segmentation experiments on synthetic and real microarray images show that the proposed method is effective and feasible for the foreground segmentation of microarray image.
2016 Vol. 25 (4): 139-148 [
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12
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149
Computer Simulations of Hemodynamic Effects of Different CPR Techniques
ZENG Huang-cun, LUO Jun-qing, WU Xiao-min
Cardiopulmonary resuscitation is a simple and effective medical treatment for patients with sudden cardiac arrest. Most researches on CPR are animal experiments and human trials. Because there are many confounding factors present in experiments, conflicting conclusions are often drawn. In this paper, we followed the line of theoretical research on CPR. Then, we adapted previous CPR models, simulated rive CPR techniques using the adapted model, and compared their hemodynamics in the same test system. Through the comparison, the simulation results agree quite well with experimental data. The simulation results show that when external counter pulsation is applied during CPR, it may improve the cardiac output and increase the diastolic aortic pressure. Yet, external counter pulsation is not widely used during CPR. We think that this experiment deserves further research. Given the benefits of models and simulations, our adapted model may be a useful tool in CPR research.
2016 Vol. 25 (4): 149-156 [
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14
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157
Mechanical Performance of Cranial Bone in Impact Protection of Woodpecker Brain: A Finite Element Study
WANG Li-zhen, FAN Yu-bo
Human head impact injuries caused by a sudden impact force are very common in aviation lifesaving, car crash accident, war or sports activities. Yet, an intriguing example of nature is woodpecker which is free from head injury even it drums trunk continually at a speed of about 6-7 m/s and a deceleration of about 1000 g. Woodpecker must have special characteristics to attenuate repetitive impact force to sustain rapid pecking without brain injury. In this study, the effect of mechanical property of cranial bone on the brain during impact was investigated using the finite element (FE) approach. It was demonstrated that the pressure, Von-Mises stresses and shear stress at the same point on the posterior of woodpecker's brain were decreased greatly compared with hoopoe and lark. It was stated that the higher strength of woodpecker's cranial bone might play an important role for preventing woodpecker's head injury.
2016 Vol. 25 (4): 157-161 [
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14
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162
Influence of Junction Angle Changed Models on Hemodynamic of Coronary Artery Bypass Graft
LIU Zhao-miao, GAO Li-dan, SHI Yi
The restenosis after coronary artery bypass graft (CABG) is attributed to the formation of intimal hyperplasia (IH) at the anastomosis, which is closely related to hemodynamic depend on the geometric model. In order to give a reasonable assessment of the surgery effect and judge the long-term patency rate, the hemodynamic of CABG surgery program is compared with that of surgery design of the junction angle changed. Based on in-vivo CT coronary angiography datasets, the individual geometric model of CABG reconstructed instead of idealized geometric models are applied to simulate the real physiological blood flow utilizing pulsatile flow boundary waveforms in the present study. The simulation results show that the maximum wall shear rate(WSS) value is at the bottom of anastomosis. Moreover, the stagnation zone growing gradually with the greater angle downstream the anastomosis is prone to form the IH, which is consistent with clinical observation. It is proved that the surgery being better suited to maintain graft patency is successful.
2016 Vol. 25 (4): 162-167 [
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15
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168
Mechanical Analysis of Foot Plantar Fascia in Normal Walking Condition
GU Yao-dong, LI Zhou-cheng
Foot plantar fascia is a kind of important tissue in stabilizing the longitudinal arch of human foot. Direct measurement to monitoring the mechanical situation of plantar fascia at human locomotion is very difficult. The purpose of this study is to construct a three-dimensional finite element model of the foot to calculate the internal stress/strain value of plantar fascia during different stages of the gait. The simulated stress distribution of plantar fascia was the lowest at heel-strike, which concentrated on the medial side of calcaneal tubercle. The peak stress of plantar fascia was appeared at push-off, and the value was more than 5 times of the heel-strike position. Current FE model was able to explore the plantar fascia tension trend at the main subphases of the foot. More detailed fascia models and intrinsic muscle forces could be developed in the further study.
2016 Vol. 25 (4): 168-178 [
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28
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Review
179
Portable Wireless ECG Monitor with Fabric Electrodes
ZHOU Ping, LI Zhou-cheng, WANG Feng, JIAO Hong-yu
A portable and comfortable wireless ECG monitoring system composed of fabric electrodes and a monitoring terminal was proposed, which is essential to continuous ECG monitoring. The ECG signal acquired could be processed and stored in the monitoring terminal. The HR was got and transmitted to any devices through a Bluetooth interface. The experimental results in resting and walking showed that the ECG monitoring system could acquire the ECG signal steadily, continuously and precisely.
2016 Vol. 25 (4): 179-189 [
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14
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