|
|
Computer Simulations of Hemodynamic Effects of Different CPR Techniques |
ZENG Huang-cun1,2, LUO Jun-qing1, WU Xiao-min1 |
1. Department of Biomedical Engineering, South China University of Technology, Guangzhou 510641, China; 2. Department of Information Technology, Guangdong Teachers' College of Foreign Language and Arts, Guangzhou 510640, China |
|
|
Abstract Cardiopulmonary resuscitation is a simple and effective medical treatment for patients with sudden cardiac arrest. Most researches on CPR are animal experiments and human trials. Because there are many confounding factors present in experiments, conflicting conclusions are often drawn. In this paper, we followed the line of theoretical research on CPR. Then, we adapted previous CPR models, simulated rive CPR techniques using the adapted model, and compared their hemodynamics in the same test system. Through the comparison, the simulation results agree quite well with experimental data. The simulation results show that when external counter pulsation is applied during CPR, it may improve the cardiac output and increase the diastolic aortic pressure. Yet, external counter pulsation is not widely used during CPR. We think that this experiment deserves further research. Given the benefits of models and simulations, our adapted model may be a useful tool in CPR research.
|
Received: 20 March 2016
|
Corresponding Authors:
ZENG Huang-cun.
E-mail: R 318.01
|
|
|
|
[1] Shuster M, Lim S, Deakin C, et al. Part 7: CPR techniques anddevices: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations[J]. Circulation, 2010, 122(suppl 2):S338-S344. [2] Manchanda A, Soran O. Enhanced external counterpulsation and future directions[J]. Journal of the American College of Cardiology, 2007, 50(16):1523-1531. [3] Arora R, Chou T, Jain D, et al. The multicenter study of enhanced external counterpulsation (MUST-EECP): effect of EECP on exercise-induced myocardial ischemia and anginal episodes[J]. Journal of the American College of Cardiology, 1999, 33(7):1833-1840. [4] Yuan H, Jiang L, Xu W, et al. Hemodynamics of active compression-decompression CPR with enhanced external counterpulsation and the inspiratory impedance threshold valve[J]. Emergent Medical Journal of Lingnan, 2007, 12(5):326-328. [5] Yannopoulos D, Halperin H, Hopkins J, et al. Lower extremity counterpulsation during the decompression phase of CPR improves hemodynamics and provides continuous forward carotid blood flow[J]. Circulation, 2007, 16(11):485. [6] Babbs C. CPR techniques that combine chest and abdominal compression and decompression: hemodynamic insights from a spread sheet model[J]. Circulation, 1999, 100:2146-2152. [7] Babbs C. Effects of an impedance threshold valve upon hemodynamics in Standard CPR: Studies in a refined computational model[J]. Resuscitation, 2005, 66:335-345. [8] Xu L, Wu X, Zhang Y, et al. The optimization study on time sequence of enhanced external counter-pulsation in AEI-CPR[J]. Journal of Computers, 2009, 4(12):1243-1248. [9] Xu L, Wu X, Zhang Y. Near-optimal waveforms for improving hemodynamic effects during EDCPR[C]. IEEE Proceedings of International Symposium on Computational Intelligence and Design,Wuhan, China, 2008: 362-365. [10] Luo J, Wu X, Zeng H, et al. Computer simulations of hemodynamic effects of EECP during AEI-CPR[C]. IEEE Proceedings of International Conference on Bioinformatics and Biomedical Engineering, Chengdu, China, 2012: 1-3. [11] Adams C, Martin G, Rivers E, et al. Hemodynamics of interposed abdominal compression during human cardiopulmonary resuscitation[J]. Academic Emergency Medicine, 1994, 1(5):498-502. [12] Barranco F, Lesmes A, Irles J, et al. Cardiopulmonary resuscitation with simultaneous chest and abdominal compression:comparative study in humans[J]. Resuscitation, 1990, 20(1):66-67. [13] Berryman C, Phillips G. Interposed abdominal compression-CPR in human subjects[J]. Annals of Emergency Medicine, 1984, 13(4):226-229. [14] Cohen T, Tucker K, Lurie K, et al. Active compression-decompression. A new method of cardiopulmonary resuscitation[J]. Journal of the American Medical Association, 1992, 67(21):2916-2923. [15] Shultz J, Coffeen P, Sweeny M, et al. Evaluation of standard and active compression-decompression CPR in an acute human model of ventricular fibrillation[J]. Circulation,1994, 89(2):684-693. |
|
|
|