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Study on Spot Addressing and Segmentation Method for Microarray Image |
LIU Quan-jin1,2, ZHU Xing-yue1, ZHAO Zhi-min1 |
1. College of Science, Nanjing University of Aeronautics and Astronautics, Jiangsu Province Nanjing 210016, China; 2. School of Physics & Electronic Engineering, Anqing Normal College, Anhui Province Anqing 246011, China |
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Abstract This paper presents a novel method of spot addressing and segmentation about the foreground segmentation of microarray image. In this paper, a spot addressing method based on particle swarm optimization (PSO), algorithm is proposed to have a further search for the center coordinate and radius of the spot whose region is determined by the projection method. Then, a foreground segmentation method is put forward to make the spot foreground segmentation based on the center coordinate and radius of the spot. The spot addressing and segmentation experiments on synthetic and real microarray images show that the proposed method is effective and feasible for the foreground segmentation of microarray image.
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Received: 20 September 2016
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Fund:National Natural Science Foundation of China; grant number:61475071; grant sponsor: Funding for Outstanding Doctoral Dissertation in NUAA; grant number:BCXJ14-13 |
Corresponding Authors:
ZHAO Zhi-min. E-mail: zhaozhimin@nuaa.edu.cn
E-mail: R 318.04
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