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| Phase-contrast Imaging Simulation Based on a Micro-CT System |
| GUI Jian-bao, ZOU Jing, RONG Jun-yan, HU Zhan-li, ZHANG Qi-yang, ZHENG Hai-rong, XIA Dan |
| Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055 , China |
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Abstract Propagation-based phase-contrast imaging was simulated based on paraxial Fresnel-Kirchoff diffraction integral and spherical wave illumination. Under a developed micro-CT system parameters, the effects of focal-spot size and imaging geometry on phase-contrast imaging have been investigated using a 2-mm-thickness polystyrene edge phantom. An equivalent mono-energy was used to substitute the polychromatic spectrum of the micro-focus X-ray source. To consider effects of focal-spot size and detector resolution, the obtained phase-contrast image with an ideal point source was convolved with source intensity distribution and point spread function of detector. Simulations show reasonable influences of the two parameters which are in good agreement with experimental results.
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Received: 15 June 2016
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Corresponding Authors:
GUI Jian-bao. E-mail: jb.gui@siat.ac.cn
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