Establishment of a Fast Quality Assurance Method for Three-dimensional Afterloading Treatment Plan

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Abstract Objective: To study the correlation between tumor size, radiation source intensity, prescription dose, and source dwell time in afterloading treatment plan, and to establish a rapid quality control method for afterloading treatment plan. Methods: A total of 181 patients with gynecological tumor were enrolled in our hospital. A total of 84 patients were installed with three tubes of Fletcher' applicator, 58 patients with single uterine tube and 39 patients with vaginal applicator. Each patient was scanned with CT before treatment, and the target area and organs were delineated by doctors. The treatment plan was optimized by IPSA. The planned source intensity, prescription dose, source residence time and tumor volume of each case were recorded and the CI, RV, and k value were calculated, The CI distribution characteristics and the relationship with RV value were analyzed. In addition, 46 cases of gynecological tumor patients' afterloading plan used this method for quality control verification. Results: The CI of the three kinds of applicators was normal distribution. The average Ci of Fletcher applicator was 0.720±0.067, k=1394, r=0.894, the average CI of Fletcher applicator was 0.697±0.076, k=1428, r=0.940, the average CI of vaginal applicator was 0.742±0.067, k=1362, r=0.909. Conclusion: Using this method, we could quickly evaluate the target volume, radiation source intensity, prescription dose and treatment time, to determine the cause of deviation according to the feedback results, ensuring that the afterloading treatment plan can be implemented efficiently quickly, and accurately in accordance with the clinical requirements.

Key words： brachytherapy simulated annealing reverse plan rapid quality control three-dimensional (3D) loading

Received: 05 July 2019

PACS:

TP 391.4

Corresponding Authors: JI Tian-long. E-mail: 18040095029@163.com

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	JI Tian-long
	ZHAO Jing
	SHEN Hao
	LI Guang

Cite this article:

JI Tian-long,ZHAO Jing,SHEN Hao, et al. Establishment of a Fast Quality Assurance Method for Three-dimensional Afterloading Treatment Plan[J]. Chinese Journal of Biomedical Engineering, 2019, 28(3): 105-112.

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http://manu32.magtech.com.cn/Jwk_zgswyx_en/EN/ OR http://manu32.magtech.com.cn/Jwk_zgswyx_en/EN/Y2019/V28/I3/105

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