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The Analysis of SNP within GPR26 Gene and Tumor-Associated Latent Loci |
WU Bin1, QU Fang1, CAO Peng-rong2, HU Jing1, YI Yin-sha1, ZHA Wen-ting1, LV Yuan1 |
1. Medical College of Hunan Normal University, Hunan Province Changsha 410006, China; 2. Changsha Yingrun Biotechnology Inc., Hunan Province Changsha 410013, China |
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Abstract This study aims to investigate the association of SNPs with tumor-associated latent loci. By analyzing the effect of gene mutations on the structure and function of proteins with the database, to speculate the destructive mutants. It was found that individuals with the genotype of the five key SNP loci were more susceptible to tumors; these specific markers can be used as a molecular marker to determine the susceptibility of a tumor to the individual, and to diagnose the population with high risk of tumor; and rs201154887 can be used as a new disease molecular marker.
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Received: 20 March 2017
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Fund:Graduate Student Research and Innovation Project of Hunan Province; grant number: CX2015B182;Educational Reform Project of Hunan Provincial Department of Education |
Corresponding Authors:
ZHA Wen-ting, Lv Yuan. E-mail: 183259829@qq.com, ly598598@126.com
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