|
|
|
| Research Progress on the Influence of Trace Elements on Osteoarthritis |
| LU Fang, LI Yu-yan, ZHANG Min, WANG Shuang-ge |
| Jilin Kingmed for Clinical Laboratory Co., Ltd., Changchun Jilin 130000, China |
|
|
|
|
Abstract Osteoarthritis is a common clinical chronic degenerative disease with a gradually increasing morbidity as the population ages. The pathogenesis of the disease always maintained as a focus of clinicians' research. At present, the etiology and pathogenesis of osteoarthritis are far from clear. The attack of the disease has something to do with the patient's joint inflammation, trauma and genetic factors, which is a result of joint action of multiple factors. Trace elements are elements indispensable in the growth and development of the body. Despite it stiny content in the human body, it produces powerful biological effects and plays an important role in the growth and metabolism of the body. This paper studies the relevance between trace elements and osteoarthritis.
|
|
Received: 12 January 2022
|
|
|
|
Corresponding Authors:
WANG Shuang-ge. E-mail: 516273533@qq.com
|
|
|
|
[1] Getelman MH.Editorial commentary: Stem cell treatment for knee osteoarthritis: Holy grail or tin cup[J]? Arthroscopy, 2019, 35(1):289-290.
[2] Qu Z, Yang F, Hong J, et al.Causal relationship of serum nutritional factors with osteoarthritis: a Mendelian randomization study[J].Rheumatology(Oxford), 2021, 60(5):2383-2390.
[3] Tada K, Toribatake Y, Yamamoto D, et al.Tin ring splint treatment for osteoarthritis of the distal interphalangeal joints[J].Hand(N Y), 2019, 14(5):684-688.
[4] Zhang R, Guo H, Yang X, et al.Potential candidate biomarkers associated with osteoarthritis: Evidence from a comprehensive network and pathway analysis[J].J Cell Physiol, 2019, 234(10):17433-17443.
[5] Jin ZK, Yang Y, Xu CX, et al.Outcomes of total knee arthroplasty in the adult Kashin-Beck disease with severe osteoarthritis[J].IntOrthop, 2019, 43(2):323-331.
[6] Li Z, Zhang R, Yang X, et al.Analysis of gene expression and methylation datasets identified ADAMTS9, FKBP5, and PFKBF3 as biomarkers for osteoarthritis[J].J Cell Physiol, 2019, 234(6):8908-8917.
[7] Wang Y, Wu C, Yang Y, et al.Preliminary Exploration of hsa_circ_0032131 levels in peripheral blood as a potential diagnostic biomarker of osteoarthritis[J].Genet Test Mol Biomarkers, 2019, 23(10):717-721.
[8] Wang Y, Wu C, Zhang F, et al.Screening for differentially expressed circular RNAs in the cartilage of osteoarthritis patients for their diagnostic value[J].Genet Test Mol Biomarkers, 2019, 23(10):706-716.
[9] Qi X, Yu F, Wen Y, et al.Integration of transcriptome-wide association study and messenger RNA expression profile to identify genes associated with osteoarthritis[J].Bone Joint Res, 2020, 9(3):130-138. |
|
|
|
