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Advances in the Application of Radiomics in Colorectal Cancer |
ZHOU Xue-zhi1,3, WEI Wei2,3, LIU Zhen-yu3, WANG Shuo3, TIAN Jie1,3,4 |
1. Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education, School of Life Science and Technology, Xidian University, Xi'an 710126, China;
2. School of Electronics and Information, Xi'an Polytechnic University, Xi'an 710048, China;
3. CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing 100191, China;
4. Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Medicine, Beihang University, Beijing 100191, China |
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Abstract Medical images contain a great deal of information that cannot be recognized by the human eye. It may not only fully express the heterogeneity of the tumor, but also reflect important information such as prognosis information of patients. With the development of image processing and artificial intelligence technology, an emerging field called "radiomics" has become a research hotspot, aiming to assist doctors to make decisions or to solve the thorny problems in clinical practice by advanced image analysis technology. In this paper, taking applications of radiomics in colorectal cancer as an example, we introduced the basic principle and technology of radiomics followed by studies focusing on different clinical questions during treatment cycle, including assessment and prediction of the pathological response status after neoadjuvant chemoradiotherapy, the decision of operative plan and the survival analysis after operation. We believe that advances in medical image analysis will promote the development of precision medicine.
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Received: 15 November 2020
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Fund:grant sponsor: Innovation Project of Medicine and Health Science and Technology of Chinese Aceademy of Medical Sciences; grant number: 216-I2M-3-018 |
Corresponding Authors:
TIAN Jie. E-mail: jie.tian@ia.ac.cn
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