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Analysis and Interpretation of Detection Results of Novel Coronavirus Nucleic Acids and Specific Antibodies |
Dongliang Li*, Jia Ye, Yunhua Yu, Guoqing Yu, Chuanshen Jiang, Xianliang Lin, Wenfeng Lin, Youguang Lu |
The 900th Hospital of the Joint Logistics Support Force of Chinese PLA, Fuzhou 350000, China |
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Abstract The novel coronavirus (2019 novel coronavirus, 2019-nCoV) is a newly emerged virus. Therefore, the nucleic acid detection technology and serum immunological detection technology established urgently in emergencies have certain defects inevitably. The efficiency of nucleic acid and antibody detection varies at different stages of disease progression of the novel coronavirus disease (COVID-19). If the two can be used in combination and the results of the analysis can be comprehensively judged, they can be combined to monitor the viral load and disease progress better and improve the diagnostic efficiency. Based on the author's application experience, this article analyzes and interprets eight common modes of combined detection of nucleic acids and specific antibodies in order to provide a reference for the clinical diagnosis and treatment of COVID-19.
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