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| Long-term Prediction of Bone Density Distribution for Retained Intramedullary Nail |
| WANG Chao1, WANG Li-zhen1, FAN Yu-bo1,2 |
1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China;
2. State Key Laboratory of Virtual Reality Technology and Systems, Beihang University, Beijing 100191, China |
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Abstract Intramedullary nailing is a standard treatment for adult long bone fracture. Previous numerous animal, biomechanical and clinical studies have documented the short-term performance of the intramedullary nails; however, the long-term influence of the nails on the change of bone density distribution is still not fully understood. According to bone remodeling theory, a set of computational algorithms was implemented in the finite element model to predict the bone density distribution for retained intramedullary nail. The bone density was recorded to observe the progression of remodeling. The results show that the effect of intramedullary nail on the Gruen zone 4 and 5 of femur is small, while the effect on the Gruen zone 1, 2 and 6 is greater than other zones. This simulation indicates that intramedullary nail plays a significant role in the long-term bone density distribution after surgery.
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Received: 22 September 2018
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| Fund:National Natural Science Foundation of China; grant number:10925208 and 11120101001; grant sponsor: National Basic Research Program of China; grant number: 2011CB710901 |
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Corresponding Authors:
FAN Yu-bo. E-mail: yubofan@buaa.edu.cn
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