1. Institute of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Jinan Shandong 250061, China; 2. Air Force Medical Center, PLA, Beijing 100142, China; 3. Medical Big Data Research Center, Chinese PLA General Hospital, Beijing 100853, China; 4. Department of Medical Engineering Management, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan Shandong 250021, China
Comparison of Heart Rate Variability between Normoxia and Hypobaric Hypoxia Exposure
1. Institute of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Jinan Shandong 250061, China; 2. Air Force Medical Center, PLA, Beijing 100142, China; 3. Medical Big Data Research Center, Chinese PLA General Hospital, Beijing 100853, China; 4. Department of Medical Engineering Management, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan Shandong 250021, China
摘要This study aimed to use the sample entropy (SampEn) method to compare the difference between normoxia and hypobaric hypoxia exposure in heart rate variability. Eight healthy male volunteers were included in this research. For each subject, electrocardiography and finger pulse signal were recorded to obtain the heart rate time series. The SpO2 signal was collected at the same time. In normoxia or hypobaric hypoxia 4300 m section, the segment of RR time series from the second 5 min episode (from the 6th to the 10th min) was chosen for the SampEn calculation. The differences between normoxia and hypobaric hypoxia states were analyzed. Results showed that a significant difference exists in SampEn between two states (normoxia 0.54±0.05 vs hypobaric hypoxia 4300 m exposure 0.46±0.05), indicating the regulatory mechanisms of autonomic nervous system from a nonlinear perspective.
Abstract：This study aimed to use the sample entropy (SampEn) method to compare the difference between normoxia and hypobaric hypoxia exposure in heart rate variability. Eight healthy male volunteers were included in this research. For each subject, electrocardiography and finger pulse signal were recorded to obtain the heart rate time series. The SpO2 signal was collected at the same time. In normoxia or hypobaric hypoxia 4300 m section, the segment of RR time series from the second 5 min episode (from the 6th to the 10th min) was chosen for the SampEn calculation. The differences between normoxia and hypobaric hypoxia states were analyzed. Results showed that a significant difference exists in SampEn between two states (normoxia 0.54±0.05 vs hypobaric hypoxia 4300 m exposure 0.46±0.05), indicating the regulatory mechanisms of autonomic nervous system from a nonlinear perspective.
通讯作者:
Yuanyuan Liu, Department of Medical Engineering Integration, School of Control, Shandong University, Jinan Shandong 250061, China. E-mail address: liuyy@sdu.edu.cn
引用本文:
Yuanyuan Liu, Zhengtao Cao, Mengsun Yu, Jun Yang, Binhua Wang, Yingying Ma. Comparison of Heart Rate Variability between Normoxia and Hypobaric Hypoxia Exposure[J]. 中国生物医学工程学报(英文版）, 2020, 29(2): 25-30.
Yuanyuan Liu, Zhengtao Cao, Mengsun Yu, Jun Yang, Binhua Wang, Yingying Ma. Comparison of Heart Rate Variability between Normoxia and Hypobaric Hypoxia Exposure. Chinese Journal of Biomedical Engineering, 2020, 29(2): 25-30.
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