Abstract：In the application of RNAi technology, it is an essential step to design siRNA applicable to target gene. At present, there are many researches and conclusions on siRNA design. This paper aims to the influences of mRNA secondary structure or siRNA antisense-strand secondary structure on siRNA silence efficiency. The paper also discusses the problems and sets out further insights in the research.
. [J]. 中国生物医学工程学报(英文版）, 2015, 23(4): 179-184.
SUN Ying, GUI Jian-bin, CHEN Zhao-xue. The Influence of RNA Secondary Structure on the Efficiency of siRNA Silencing. Chinese Journal of Biomedical Engineering, 2015, 23(4): 179-184.
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