Application of Phase Angle Measurement through Bioelectrical Impedance Analysis in the Diagnosis of Sarcopenia in the Elderly-Relationship between Phase Angle and Sarcopenia
ZHAO Hong1, ZHOU Jing2, HE Xu1
1. Yiyang Medical College, Yiyang Hunan Province 413002, China; 2. Affiliated Hospital of Yiyang Medical College, Yiyang Hunan Province 413002, China
Application of Phase Angle Measurement through Bioelectrical Impedance Analysis in the Diagnosis of Sarcopenia in the Elderly-Relationship between Phase Angle and Sarcopenia
ZHAO Hong1, ZHOU Jing2, HE Xu1
1. Yiyang Medical College, Yiyang Hunan Province 413002, China; 2. Affiliated Hospital of Yiyang Medical College, Yiyang Hunan Province 413002, China
摘要Objective: To investigate the diagnostic value of phase angle based on bioelectrical impedance method in senile sarcopenia. Methods: Clinical data from patients aged 60 and above who received treatment in our hospital from January 2023 to January 2023 were retrospectively collected and analyzed. A total of 214 cases were divided into two groups based on the presence or absence of sarcopenia. The baseline data of the two groups were compared, and multiple regression analysis was conducted to identify the independent risk factors of sarcopenia in the elderly. Additionally, the diagnostic effect of phase angle on sarcopenia in the elderly was assessed using the ROC curve analysis. Results: A total of 214 cases were included, of which 103 patients (48.131%) were diagnosed with sarcopenia, while the remaining 111 patients (51.869%) with non-sarcopenia. The results showed that the age of sarcopenia group was significantly higher than that of non-sarcopenia group (P<0.05). Additionally, total body moisture, protein, inorganic salts, body fat, phase angle, skeletal muscle mass index, grip strength and 6-m pace were significantly lower in sarcopenia group than those in non-sarcopenia group (P<0.05). Correlation and regression analyses identified phase angle, BMI, total body moisture, and body fat as independent risk factors for sarcopenia in the elderly (OR>1). ROC curve analysis showed that the areas under AUC for the phase angle, BMI, total body moisture, and body fat AUC were 0.762, 0.650, 0.685, and 0.660, respectively. The highest combined diagnostic AUC was 0.865, indicating that the combined diagnosis had a better diagnostic effect on sarcopenia in the elderly.Conclusion:Phase angle serves as an effective index for detecting sarcopenia in the elderly, which can effectively evaluate muscle mass and muscle strength. It suggests that phase angle as an easy-to-monitor indicator is conductive to a more accurate and convenient diagnosis of sarcopenia.
Abstract：Objective: To investigate the diagnostic value of phase angle based on bioelectrical impedance method in senile sarcopenia. Methods: Clinical data from patients aged 60 and above who received treatment in our hospital from January 2023 to January 2023 were retrospectively collected and analyzed. A total of 214 cases were divided into two groups based on the presence or absence of sarcopenia. The baseline data of the two groups were compared, and multiple regression analysis was conducted to identify the independent risk factors of sarcopenia in the elderly. Additionally, the diagnostic effect of phase angle on sarcopenia in the elderly was assessed using the ROC curve analysis. Results: A total of 214 cases were included, of which 103 patients (48.131%) were diagnosed with sarcopenia, while the remaining 111 patients (51.869%) with non-sarcopenia. The results showed that the age of sarcopenia group was significantly higher than that of non-sarcopenia group (P<0.05). Additionally, total body moisture, protein, inorganic salts, body fat, phase angle, skeletal muscle mass index, grip strength and 6-m pace were significantly lower in sarcopenia group than those in non-sarcopenia group (P<0.05). Correlation and regression analyses identified phase angle, BMI, total body moisture, and body fat as independent risk factors for sarcopenia in the elderly (OR>1). ROC curve analysis showed that the areas under AUC for the phase angle, BMI, total body moisture, and body fat AUC were 0.762, 0.650, 0.685, and 0.660, respectively. The highest combined diagnostic AUC was 0.865, indicating that the combined diagnosis had a better diagnostic effect on sarcopenia in the elderly.Conclusion:Phase angle serves as an effective index for detecting sarcopenia in the elderly, which can effectively evaluate muscle mass and muscle strength. It suggests that phase angle as an easy-to-monitor indicator is conductive to a more accurate and convenient diagnosis of sarcopenia.
基金资助:Scientific Research Project of Hunan Provincial Education Department; grant number: 22C1326
通讯作者:
HE Xu. E-mail: zhangxinchun0210@163.com
引用本文:
ZHAO Hong, ZHOU Jing, HE Xu. Application of Phase Angle Measurement through Bioelectrical Impedance Analysis in the Diagnosis of Sarcopenia in the Elderly-Relationship between Phase Angle and Sarcopenia[J]. 中国生物医学工程学报(英文版）, 2024, 33(3): 93-99.
ZHAO Hong, ZHOU Jing, HE Xu. Application of Phase Angle Measurement through Bioelectrical Impedance Analysis in the Diagnosis of Sarcopenia in the Elderly-Relationship between Phase Angle and Sarcopenia. Chinese Journal of Biomedical Engineering, 2024, 33(3): 93-99.
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